Those darn chemicals: Difference between revisions

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Now, if we say absolutely everything is chemicals, that feels like a game of semantics, like "all concepts are made up" -- ''yes'', technically true but not useful to what we mean to communicate. Stop defending putting that weird shit in my body.
Which feels like a game of semantics, much "all concepts are made up" -- technically true but not useful to what we mean to communicate.  
 
 
You know what I mean, stop defending putting that weird shit in my body.


And yes, if that were my game here, you would be absolutely right to call it out.
And yes, if that were my game here, you would be absolutely right to call it out.




Yet if you are saying you know exactly what chemicals are good ones and which are bad ones,
'''However''.
 
If you are saying that you know exactly what chemicals are good ones and which are the bad ones,
then you are falling right into a trap that marketers have been getting away with for ''way'' too long.
then you are falling right into a trap that marketers have been getting away with for ''way'' too long.


And if you pay only attention to the last boogymen, and cannot rank what the worst influences are,
And if you pay only attention to last year's boogymen, then
or estimate how much to care about specific ones, then you're you're actively distracting yourself from information that will actually let you live a bit healthier.
* they will continue to do so.
* you are actively distracting yourself from information that will actually let you live a bit healthier.
 
 
We need to be able to rank how bad things are,
rank which are worst influences are,
or estimate how much to care about specific ones.




One dumb point to be made is that almost ''everything'' is toxic at the right dose.
One dumb point to be made is that almost ''everything'' is toxic at the right dose.


''Every'' healthy thing in normal doses can kill you if there is enough of it.
Drink half a dozen liters of water and your body cannot compensate.
(It's not common in part because you will feel terrible and stop doing it)
 
 
 
Every healthy thing can also kill you, if you take enough,
: they just happen to make it ''difficult'', often by having a large zone where the amount still won't do much
 
Unhealthy things are just the things that do so faster,
: that do so at amounts you might not immediately think of as harmful,
: i.e. that skip that safe zone
 


Unhealthy things are just the things that do that quickly enough that they ''skip'' having a safe zone


{{comment|(the main technical reason you wouldn't take away the 'almost' is that the mechanism that kills you is sometimes considered something else. For example, drink too much coffee and it's the ''water'' that kills you, even if the caffeine would also do so later)}}
And for some things, the reason it won't kill you is that something else gets to you before another.
For example, drink too much coffee and it's the ''water'' that kills you first, not the caffeine.
 




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==Toxin, poison, venom==
==Toxin, poison, venom==


===More technically===
<!--
<!--
The following is only really useful to thosedoing medicine, biology, or chemistry,
or something else where being more precise.


In everyday use, the general sense of 'something you don't want in you'
The following distinctions are only really useful to those doing medicine, biology, or chemistry,
''that guy'' at a party, or something else where you want to be more precise.




In everyday use, the general sense of 'something you don't want in you' is enough.




Poisons are any chemical substances that impact biological functions in other organisms




Toxins are biologically produced chemical substances that impact biological functions in other organisms.
Poisons are any '''chemical''' substances that impact biological functions in other organisms


So you could think of a toxin is a naturally orcurring poison.
Toxins are '''biologically produced''' chemical substances that impact biological functions in other organisms.


Using that definition, nothing synthesized is toxin. Chemists may use '''toxicant'''s for that.


So you can think of
* poisions as general
* toxins as natural naturally occurring poisons


Using that definition, nothing synthesized is toxin. Chemists sometimes use '''toxicant'''s for that.


Venom versus poison is also about direction:
 
 
Adding '''venom''' (versus poison/toxin) adds ''direction'' to the definitions:
: if you bite it and it's bad for you, its poison. If it's secreted, it's poison.
: if you bite it and it's bad for you, its poison. If it's secreted, it's poison.
: If it bites you and it's bad, it's venomous.  
: If it bites you and it's bad, it's venomous.  
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-->
-->
 
===More practically===
 
 
 
==LD50==
<!--
<!--
* Venoms tend to be defensive for animals, poisons/toxins as defensive for plants,


In toxicology, LD50 is the '''median lethal dose'': the amount that would kill 50% of the the population.
* ...and as far as biology is concerned, we humans are just another organism in the mix of many others,
{{comment|(well, half of a test population, which is generally not a lot of them for ethical reasons, so has statistical footnotes)}}
: our body can deal with small amounts of any, or we would not be viable to live very long


* so while ''anything'' is bad in large amounts...
: venoms more easily so because if they weren't, they would be pointless


If you want a level to ''really'' stay away from, it's going to be a morbid definition any which way,
* ...at the same time, most of these are harmless in smaller amounts
and LD50 is a "''definitely'' stay away from these levels of the thing, but wouldn't wipe us out immediately" figure.


They still tax your body, so why would you do that ''knowingly'',
but also you'll be okay.




Used for toxins, radiation, pathogens.
-->


===...except: bioaccumulation===


For chemical and biological things, the unit is often mass of substance per mass of test subject,
<!--
often in mg/kg, though the prefix varies from nanograms and micrograms (for things with high toxicity),
...the above holds for things that leave your system quickly.  
to milligrams and grams (for things with low toxicity, e.g. paracetamol).
 
 
Such a figure isn't always a directly meaningful figure.
 
Say, coffee's LD50 is 192 mg/kg, but of ''what''? We don't eat coffee directly, and in terms of liquid coffee (which is mostly water) it's on the order of 25 liters.
...which actually makes the coffee mostly irrelevant. as [[water poisoining]] (LD50 quoted as 90g/kg) would be an issue way before the caffeine would be.
 


Which is most things, but not all.


It also does not directly consider whether something is fast-acting or not, digested versus bioaccumulated, and such.


The coffee example is additionally interesting in that you would likely secrete it quickly enough.


The two terms to know here are:


* '''Bioaccumulation'''[https://en.wikipedia.org/wiki/Bioaccumulation] - chemicals building in an organism because it can't break it down, or excrete it, faster than it is ingested.


https://en.wikipedia.org/wiki/Median_lethal_dose
-->
==Bioaccumulation==
<!--
'''Bioaccumulation'''[https://en.wikipedia.org/wiki/Bioaccumulation] - chemicals building in an organism because it can't break it down or excrete it faster than it is ingested.


* '''Biomagnification'''[https://en.wikipedia.org/wiki/Biomagnification] is the rest of the food chain making things a little worse:
consider that what you eat (plants or animal) also eat. If they eat the thing as well, and you ingest it directly ''and/or'' this other way, there are more ways in and buildup goes faster than you might think.


'''Biomagnification'''[https://en.wikipedia.org/wiki/Biomagnification] - Roughly: if not only you eat the thing, but lots of things ''you'' eat (plants or animals) also eats the thing, it goes faster. It's more of the food chain making things a little worse.






Things that cannot be broken down will do very little to leave.


Things that cannot be broken down will do very little to leave. We will typically know this as "don't eat or touch, ever".
We will typically know this as "don't eat or touch, ever".
Even if the harm per volume is tiny, we consider it poison, because even if a little ingestion is fine, we want to know not to do it in general.




Things that ''can'' be broken down, or moved out, are only bioaccumulative only if we ingest it faster than we can break down or move out.
Things that ''can'' be broken down, or moved out, can still be bioaccumulative, but only if we ingest it faster than we can break down or move out.


Your body will still have a harder time than if you never put them in you, but it is unlikely to be the thing you'll die of.
Your body will still have a harder time than if you never put them in you, but it is unlikely to be the thing you'll die of (the process taxing your body may still make it an indirect effect).




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See also:
* [https://pubmed.ncbi.nlm.nih.gov/17477364/ Mechanisms of mercury disposition in the body]
* [https://www.urmc.rochester.edu/labs/rand/projects/methylmercury-metabolism-elimination.aspx Methylmercury Metabolism and Elimination Status (MerMES) in Humans ]
* [https://inchem.org/documents/cicads/cicads/cicad50.htm Elemental Mercury and Inorganic Mercury Compounds: Human Health Aspects]
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988285/ Environmental Mercury and Its Toxic Effects]




-->


==LD50==
<!--


In toxicology, LD50 is the '''median lethal dose'': the amount that would kill 50% of the the population.
{{comment|(well, half of a test population, which is generally not a lot of them for ethical reasons, so has statistical footnotes)}}




See also:
If you want a level to ''really'' stay away from, it's going to be a morbid definition any which way,
* [https://pubmed.ncbi.nlm.nih.gov/17477364/ Mechanisms of mercury disposition in the body]
and LD50 is a "''definitely'' stay away from these levels of the thing, but wouldn't wipe us out immediately" figure.
* [https://www.urmc.rochester.edu/labs/rand/projects/methylmercury-metabolism-elimination.aspx Methylmercury Metabolism and Elimination Status (MerMES) in Humans ]
 
* [https://inchem.org/documents/cicads/cicads/cicad50.htm Elemental Mercury and Inorganic Mercury Compounds: Human Health Aspects]
 
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988285/ Environmental Mercury and Its Toxic Effects]
 
Used for toxins, radiation, pathogens.
 
 
For chemical and biological things, the unit is often mass of substance per mass of test subject,
often in mg/kg, though the prefix varies from nanograms and micrograms (for things with high toxicity),
to milligrams and grams (for things with low toxicity, e.g. paracetamol).  
 
 
Such a figure isn't always a directly meaningful figure.
 
Say, coffee's LD50 is 192 mg/kg, but of ''what''? We don't eat coffee directly, and in terms of liquid coffee (which is mostly water) it's on the order of 25 liters.
...which actually makes the coffee mostly irrelevant. as [[water poisoining]] (LD50 quoted as 90g/kg) would be an issue way before the caffeine would be.
 
 
 
It also does not directly consider whether something is fast-acting or not, digested versus bioaccumulated, and such.
 
The coffee example is additionally interesting in that you would likely secrete it quickly enough.
 




https://en.wikipedia.org/wiki/Median_lethal_dose
-->
-->


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===E numbers===
===E numbers===


'''E numbers just means it's tested'''
'''E numbers just means it's tested'''.


E numbers tend to mostly be things commonly used as food additives.
It is mostly things commonly used as food additives - so that we can quantify how to use them safely.
 
And that is a large part of ''why'' we tested it: to quantify how to use them safely.




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===What's in a name?===
<!--
Selling to a natural crowd?
"Natural pressed extract from Helianthus annuus" sounds better than "triglycerides" (that's sunflower oil, by the way)
Selling to a fancy sscientific crowd?
Call it a micellar aqueous soap. That's actually most of them, it happens to be '[https://en.wikipedia.org/wiki/Micellar_solution tiny bits suspended in something else]' (of specifically [https://en.wikipedia.org/wiki/Amphiphile amphipathic] lipids, but almost all soaps qualify)
-->
===The things you actually probably want to be there===
<!--
[https://en.wikipedia.org/wiki/Potassium_metabisulfite Potassium metabisulfite], in my wine? Why would you add something that amounts to adding disinfectant?
Well, it helps keep the taste. And color. And avoids botulism. So is also a great way to clean the wine making tools.
And yes, you want to . So it's well studied. E224, to be specific.
And yes, this is one of the sources of winey headaches, in perhaps 1% of us that are sensitive.
[https://en.wikipedia.org/wiki/Lecithin Lecithin] emulsifiers, are they necessary?
If you like stirring a lot, no.
But most of us will think our mayo, peanut butter, and yoghurt, and many other things to be worse without it.
Some people will unnecessarily throw it out, particularly if other products don't do this.
-->
=Some things worth talking about - mixed=
===Volatile organic compound (VOC)===
<!--
Volatile organic compounds are those that are
* organic compound - which is a [https://en.wikipedia.org/wiki/Organic_compound very wide category]
* volatile, meaning [https://en.wikipedia.org/wiki/Volatility_(chemistry) it evaporates quickly] (at room temperature)
This can be a feature, or entirely neutral - it describes commuication between animals and plants, and odor carriers such as perfumes,
or both, e.g. just describing the thing that makes leaves or fruits or tree have a particular smell (e.g. [https://en.wikipedia.org/wiki/Isoprene isoprene] for oaks, poplars, eucalyptus, [https://en.wikipedia.org/wiki/Limonene limonene] for lemons).
Because 'organic' is so wide,
it includes a bunch of things which are fine,
but also be something you don't want, e.g. with some causing allergic, respiratory, or immune effects.
So in particularly human-made VOCs are regulated.
Not because they're all immediately toxic - many are not - but because of potential chronic effects.
Recently, a reason you may be looking for this term is indoor VOCs, as reported by some air quality sensors.
(most sensors are actually much too selective, but reporting some of them is better than none, I suppose).
Indoor VOCs are starting to get regulated more, also to regulate VOCs emitted from products.
-->


[[Category:Cooking]]


=Some things worth talking about=


===Pesticides===
===Pesticides===
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-cide means kill. Pest means 'things we don't like in our crops'.
-cide means kill. Pest means 'things we don't like in our crops'.


 
Is it really that mind-readingly selective?  
Is it really that mind-readingly selective? Nope.
 
If pesticides ward off insects, why wouldn't they hurt us, or they environment?
If pesticides ward off insects, why wouldn't they hurt us, or they environment?


They do.
They do hurt us and the environment.


Worst case, it's basically a low level of poison, selective only in the sense that to us larger creatures it's something we can process, whereas to smaller creatures it's overwhelming.


There is a grey area around pesticides, for various reasons.
There is a grey area around pesticides, for various reasons.




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Parabens are metabolized, so low concentrations are unlikely to contribute.
Parabens are metabolized, so low concentrations are unlikely to contribute.
-->
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=Some bad names=





Latest revision as of 12:09, 21 March 2024

This article/section is a stub — some half-sorted notes, not necessarily checked, not necessarily correct. Feel free to ignore, or tell me about it.

BIG RED TEXT HELLO: This is not health advice, or necessarily correct. Do not make health decisions based on just this. Do your own research, and not just the stuff that agrees with your opinions.



On toxicity

Everything is chemicals, and everything is toxic at high concentrations

Toxin, poison, venom

More technically

More practically

...except: bioaccumulation

LD50

Things barely worth talking about

E numbers

E numbers just means it's tested.

It is mostly things commonly used as food additives - so that we can quantify how to use them safely.


They get short codes in the process, which is an easier shorthand to refer to the substance and the tests. This is often easier more precise and/or easier than a fancier pseudonym and/or more chemical name (things like INCI may help both ways (e.g. water is aqua) but at least tend to standardize the names used somewhat).

Such naming can also make regulation a lot easier to do, including the health testing.

While regulations apply regardless of what name you use, it can make it somewhat easier for you to recognize what's in there.



Some negative fearful snap judgment got all E numbers associated with unnatural and bad for you, because it's largely just "the set of things we tested", it mostly isn't.


A good number of them are in fact nutrition you absolutely need, or are perfectly healthy, and/or perfectly natural.

Consider:

E300 though E309 are vitamin C and E,
E101 is vitamin B2 used as coloring,
E160c is pepper extract, mostly used for coloring
E160a is carrot used for coloring,
E170 is calcium (basically),
E407 comes from seaweed,
E322 frequently comes from soy,
E948 is oxygen


Sure, there are also a few handfuls (out of hundreds) that I don't see having a place in my food, if I have any choice. And that was part of the point: the testing let us know we don't want it, the name lets us check more easily.


And a few that you'll probably never see - there's rarely any silver (E174) or gold (E175) in food but they're included for testing purposes, just so that you may know how safe they are when they are used in, say, cake decoration.



See also:


What's in a name?

The things you actually probably want to be there

Some things worth talking about - mixed

Volatile organic compound (VOC)

Pesticides

BPA

This article/section is a stub — some half-sorted notes, not necessarily checked, not necessarily correct. Feel free to ignore, or tell me about it.


Phtalates

This article/section is a stub — some half-sorted notes, not necessarily checked, not necessarily correct. Feel free to ignore, or tell me about it.

PFAS

PFOA

This article/section is a stub — some half-sorted notes, not necessarily checked, not necessarily correct. Feel free to ignore, or tell me about it.



Parabens

Reading off ingredient lists